2017-07-05 12:49:32Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)
proteinLength
164
geneLength
492
Gene
Coordinates
1,612,521 → 1,613,015
The protein
Catalyzed reaction/ biological activity
curvature sensitive membrane binding protein that recruits other proteins to the poles and the division septum
DivIVA is required for polar localisation of [[protein|MinC]]-[[protein|MinD]] via [[protein|MinJ]]. [Pubmed|19019154]
It also recruits [[protein|RacA]] to the distal pole of the prespore [Pubmed|12493822].
DivIVA may anchor [[protein|SpoIIE]] briefly to the assembling polar septum before [[protein|SpoIIE]] is subsequently released into the forespore membrane and recaptured at the polar septum [Pubmed|25101664]
required for the compartment-specific activation of [[protein|SigF]] [Pubmed|25101664]
activates [[protein|PrkC]] [Pubmed|25845974]
required for oriC placement during spore development [Pubmed|27059541]
curvature sensitive membrane binding protein that recruits other proteins to the poles and the division septum
DivIVA is required for polar localisation of [[protein|MinC]]-[[protein|MinD]] via [[protein|MinJ]]. [Pubmed|19019154]
It also recruits [[protein|RacA]] to the distal pole of the prespore [Pubmed|12493822].
DivIVA may anchor [SW|SpoIIE] briefly to the assembling polar septum before [SW|SpoIIE] is subsequently released into the forespore membrane and recaptured at the polar septum [Pubmed|25101664]
required for the compartment-specific activation of [[protein|SigF]] [Pubmed|25101664]
activates [[protein|PrkC]] [Pubmed|25845974]
required for oriC placement during spore development [Pubmed|27059541]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
FLAG-tag construct
GP1776 (spc, based on [SW|pGP1331]), available in [SW|Jörg Stülke]'s lab
[SW|Categories] containing this gene/protein
[SW|cell division], [SW|membrane proteins], [SW|phosphoproteins]
Gene
Coordinates on the chromosome (coding sequence)
1,612,521 -> 1,613,015
The protein
[SW|Interactions]
([[protein|MinC]]-[[protein|MinD]])-[[protein|MinJ]]-[SW|DivIVA] [Pubmed|20352045], [[protein|MinJ]] binds to the N-terminal lipid-binding domain of [SW|DivIVA] [Pubmed|23264578]
[SW|DivIVA]-[[protein|RacA]], [[protein|RacA]] binds to the C-terminal domain of [SW|DivIVA] [Pubmed|23264578]
[SW|DivIVA]-[SW|DivIVA] [Pubmed|23264578]
[[protein|Maf]]-[SW|DivIVA] [Pubmed|21564336]
[SW|DivIVA]-[[protein|ComN]] [Pubmed|22582279]
[SW|DivIVA]-[[protein|SecA]] [Pubmed|24592260]
[SW|DivIVA]-[SW|SpoIIE] [Pubmed|25101664]
Expression and Regulation
Operon
''divIVA'' [Pubmed|16420366]
Expression and Regulation
Regulation
repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
constitutively expressed [Pubmed|23701187]
Expression and Regulation
Regulatory mechanism
[SW|Spo0A]: transcription repression [Pubmed|14651647]